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动物实验显示:二甲双胍有望预防肺癌
动物实验显示:二甲双胍有望预防肺癌
发布时间 : 2019-06-20 14:39:38
美国研究人员最新发现,常用的治疗2型糖尿病的药物二甲双胍可能有利于预防因吸烟引发的肺癌。  美国国家癌症研究所的科研人员在9月份的<癌症预防研究>上介绍说,他们先将实验鼠全部暴露于亚硝胺环境中(亚硝胺是烟草尼古丁进入人体后的氧化分解物之一,属强致癌物);一段时间后,再让实验鼠分别口服(将二甲双胍溶入水中再让实验田鼠服下)或注射二甲双胍,然后将这两组实验鼠和另一组未经二甲双胍处理的实验鼠进行对照.结
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美国研究人员最新发现,常用的治疗2型糖尿病的药物二甲双胍可能有利于预防因吸烟引发的肺癌。  美国国家癌症研究所的科研人员在9月份的<癌症预防研究>上介绍说,他们先将实验鼠全部暴露于亚硝胺环境中(亚硝胺是烟草尼古丁进入人体后的氧化分解物之一,属强致癌物);一段时间后,再让实验鼠分别口服(将二甲双胍溶入水中再让实验田鼠服下)或注射二甲双胍,然后将这两组实验鼠和另一组未经二甲双胍处理的实验鼠进行对照.结
感冒片包装变更公告
感冒片包装变更公告
发布时间 : 2019-06-20 14:40:19
山东好当家海森药业有限公司复方氨酚烷胺片包装变更公告  各位尊敬的客户:  您们好!山东好当家海森药业有限公司将对11月份开始生产的10片/盒包装规格的复方氨酚烷胺片进行包装变更,  具体变更如下:  1、原来使用的“妙博士”商标变更为“颐海棠”商标;  2、小盒外观由原来的主体为蓝色变更为主体为白色;  3、小盒版面由原来一面为中文一面为英文变更为两面都是中文;  4、去掉4000608858销
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山东好当家海森药业有限公司复方氨酚烷胺片包装变更公告  各位尊敬的客户:  您们好!山东好当家海森药业有限公司将对11月份开始生产的10片/盒包装规格的复方氨酚烷胺片进行包装变更,  具体变更如下:  1、原来使用的“妙博士”商标变更为“颐海棠”商标;  2、小盒外观由原来的主体为蓝色变更为主体为白色;  3、小盒版面由原来一面为中文一面为英文变更为两面都是中文;  4、去掉4000608858销
药品GMP顺利通过
药品GMP顺利通过
发布时间 : 2019-06-20 14:43:45
药品GMP顺利通过
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药品GMP顺利通过

联磺甲氧苄啶片

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联磺甲氧苄啶片

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  LIANHUANGJIAYANGBIANDINGPIANSHUOMINGSHU

  QINGZIXIYUEDUSHUOMINGSHUBINGZAIYISHIZHIDAOXIASHIYONG

  【药品名称

  TONGYONGMINGCHENG:LIANHUANGJIAYANGBIANDINGPIAN

足球彩票   YINGWENMINGCHENG:Sulfamethoxazole,Sulfadiazine and Trimethoprim Tablets

足球彩票   HANYUPINYIN:Lianhuang Jiayangbianding Pian

  【成    份】本品为复方制剂,其组份为:磺胺甲噁唑200mg、磺胺嘧啶200mg及甲氧苄啶80mg。

  【性    状】本品为白色片。

  【适应症

  ZHUYAOYONGYUDUIBENPINMINGANDEXIJUNSUOZHIDENIAOLUGANRAN、CHANGDAOGANRAN、CHENGRENMANXINGZHIQIGUANYANJIXINGFAZUO、JIXINGZHONGERYANDENG。

  【规    格】每片含磺胺甲噁唑200mg、磺胺嘧啶200mg及甲氧苄啶80mg。

足球彩票   【YONGFAYONGLIANG】

  KOUFU CHENGRENCHANGYONGLIANGWEI:YICI2PIAN,YIRI2CI,SHOUCIJILIANGJIABEI。MANXINGZHIQIGUANYANJIXINGFAZUOLIAOCHENGZHISHAO10~14RI;NIAOLUGANRANLIAOCHENG7~10RI;XIJUNXINGLIJI5~7

  RI;JIXINGZHONGERYAN10RI。

  【不良反应

足球彩票   1. GUOMINFANYINGJIAOWEICHANGJIAN。BIAOXIANWEIYAOZHEN,YANZHONGZHEKEFASHENGSHENCHUXINGDUOXINGHONGBAN、BOTUOXINGPIYANHEDAPAOBIAOPISONGJIEWEISUOXINGPIYANDENG;YEYOUBIAOXIANWEIGUANGMINFANYING、YAOWURE、GUANJIEJIJIROUTENGTONG、FAREDENGXUEQINGBINGYANGFANYING。OUJIANGUOMINXINGXIUKE。

  2. ZHONGXINGLIXIBAOJIANSHAOHUOQUEFAZHENG、XUEXIAOBANJIANSHAOZHENG,OUKEFASHENGZAISHENGZHANGAIXINGPINXUE。HUANZHEKEBIAOXIANWEIYANTONG、FAREHECHUXUEQINGXIANG。

  3. RONGXUEXINGPINXUEJIXUEHONGDANBAINIAO。ZHEIZAIQUEFAPUTAOTANG-6-LINSUANTUOQINGMEIDEHUANZHEYINGYONGHUANGANYAOHOUYIYUFASHENG,ZAIXINSHENGERHEXIAOERZHONGJIAOCHENGRENWEIDUOJIAN。

  4. GAODANHONGSUXUEZHENGHEXINSHENGERHEHUANGDAN。YOUYUBENPINYUDANHONGSUJINGZHENGDANBAIJIEHEBUWEI,KEZHIYOULIDANHONGSUZENGGAO。XINSHENGERGANGONGNENGBUWANSHAN,GUJIAOYIFASHENGGAODANHONGSUXUEZHENGHEXINSHENGERHUANGDAN,OUKEFASHENGHEHUANGDAN。

  5. GANZANGSUNHAI。KEFASHENGHUANGDAN、GANGONGNENGJIANTUI,YANZHONGZHEKEFASHENGJIXINGGANHUAISI。

足球彩票   6. SHENZANGSUNHAI。KEFASHENGJIEJINGNIAO、XUENIAOHEGUANXINGNIAO;OUYOUHUANZHEFASHENGJIANZHIXINGSHENYANHUOSHENGUANHUAISIDEYANZHONGBULIANGFANYING。

足球彩票   7. EXIN、OUTU、WEINAJIANTUI、FUXIE、TOUTONG、FALIDENG。YIBANZHENGZHUANGQINGWEI,BUYINGXIANGJIXUYONGYAO。OUYOUHUANZHEFASHENGJIANNANSUOJUNCHANGYAN,CISHIXUTINGYAO。

  8. JIAZHUANGXIANZHONGDAJIGONGNENGJIANTUIOUYOUFASHENG。

足球彩票   9. ZHONGSHUSHENJINGXITONGDUXINGFANYINGOUKEFASHENG,BIAOXIANWEIJINGSHENCUOLUAN、DINGXIANGLIZHANGAI、HUANJUE、XINKUAIGANHUOYIYUGAN,YIDANCHUXIANJUNXULIJITINGYAO。

  10.YOUYUTMPDUIYESUANDAIXIEDEGANRAOKECHANSHENGXUEYEXITONGBULIANGFANYING,CHUXIANBAIXIBAOJIANSHAO,XUEXIAOBANJIANSHAOHUOGAOTIEXUEHONGDANBAIXINGPINXUE。YIBANBAIXIBAOJIXUEXIAOBANJIANSHAOXIQINGDU。

足球彩票   11.OUKEFASHENGWUJUNXINGNAOMOYAN, YOUTOUTONG、JINGXIANGQIANGZHI、EXINDENG。

  BENPINSUOZHIDEYANZHONGBULIANGFANYINGSUISHAOJIAN, DANCHANGLEIJIGEQIGUANBINGKEZHIMING, RUSHENCHUXINGDUOXINGHONGBAN、BOTUOXINGPIYAN、DAPAOBIAOPISONGJIEWEISUOXINGPIYAN、BAOFAXINGGANHUAISI、LIXIBAOQUEFAZHENG、ZAISHENGZHANGAIXINGPINXUEDENGXUEYEXITONGYICHANG。

  【禁    忌

足球彩票   1. DUIHUANGANLEIYAOWUGUOMINZHEJINYONG。

足球彩票   2. YOUYUBENPINZUZHIYESUANDEDAIXIE,JIAZHONGJUYOUHONGXIBAOXINGPINXUEHUANZHEYESUANYANDEQUEFA,SUOYIGAIBINGHUANZHEJINYONGBENPIN。

足球彩票   3. YUNFUJIBURUQIFUNVJINYONGBENPIN。

足球彩票   4. XIAOYU2GEYUEDEYINGERJINYONGBENPIN。

  5. GANSHENGONGNENGSUNHAIZHEJINYONGBENPIN。

  【注意事项

  1. JIAOCHAGUOMINFANYING。DUIYIZHONGHUANGANYAOCHENGXIANGUOMINDEHUANZHEDUIQITAHUANGANYAOYEKENENGGUOMIN。

  2. GANZANGSUNHAI。KEFASHENGHUANGDAN、GANGONGNENGJIANTUI,YANZHONGZHEKEFASHENGJIXINGGANHUAISI。

  GUYOUGANGONGNENGSUNHAIHUANZHEYIBIMIANHUANGANYAODEQUANSHENYINGYONG。

  3. SHENZANGSUNHAI。KEFASHENGJIEJINGNIAO、XUENIAOHEGUANXINGNIAO。RUYINGYONGBENPINLIAOCHENGZHANG,JILIANGDASHIYITONGFUTANSUANQINGNABINGDUOYINSHUI.YIFANGZHICIBULIANGFANYING。ZHILIAOZHONGZHISHAOMEIZHOUJIANCHANIAOCHANGGUI2~3CI,RUFAXIANJIEJINGNIAOHUOXUENIAOSHIJIYUTANSUANQINGNAJIYINYONGDALIANGSHUI,ZHIZHIJIEJINGNIAOHEXUENIAOXIAOSHI。SHISHUI、XIUKEHELAONIANHUANZHEYINGYONGBENPINYIZHISHENSUNHAI,YINGSHENYONGHUOBIMIANYINGYONGBENPIN。SHENGONGNENGJIANTUIHUANZHEBUYIYINGYONGBENPIN。

足球彩票   4.DUIFUSAIMI、FENGLEI、SAIQINLEILINIAOYAO、HUANGNIAOLEI、TANSUANGANMEIYIZHIYAOCHUXIANGUOMINDEHUANZHE,DUIHUANGANYAOYIKEGUOMIN。

  5. XIALIEQINGKUANGYINGSHENYONG:QUEFAPUTAOTANG-6-LINSUANTUOQINGMEI、XUEBULINZHENG、YESUANQUEFAXINGXUEYEXITONGJIBING、SHISHUI、AIZIBING、XIUKEHELAONIANHUANZHE。

足球彩票   6. YONGYAOQIJIANXUZHUYI:

足球彩票   (1)ZHOUWEIXUEXIANGJIANCHA,DUILIAOCHENGZHANG、FUYONGJILIANGDA、LAONIAN、YINGYANGBULIANGJIFUYONGKANGDIANXIANYAODEHUANZHEYOUWEIZHONGYAO;

  (2)ZHILIAOZHONGDINGQINIAOYEJIANCHA(MEI2~3RICHANIAOCHANGGUIYICI)YIFAXIANZHANGLIAOCHENGHUOGAOJILIANGZHILIAOSHIKENENGFASHENGDEJIEJINGNIAO;

  (3)GAN、SHENGONGNENGJIANCHA。

  7. MEICIFUYONGBENPINSHIYINGYINYONGZULIANGSHUIFEN。FUYONGQIJIANYEYINGBAOCHICHONGZUJINSHUILIANG,SHICHENGRENNIAOLIANGMEIRIZHISHAOWEICHIZAI1200mlYISHANG。RUYINGYONGBENPINLIAOCHENGZHANG,JILIANGDASHICHUDUOYINSHUIWAIYITONGFUTANSUANQINGNA。

  8. YANZHONGGANRANZHEYINGCEDINGXUEYAONONGDU,DUIDADUOSHUGANRANJIHUANZHEYOULIHUANGANNONGDUDA50~150mg/ml(YANZHONGGANRAN120~150mg/ml)KEYOUXIAO。ZONGHUANGANXUENONGDUBUYINGCHAOGUO200mg/ml,RUCHAOGUOCINONGDU,BULIANGFANYINGFASHENGLVZENGGAO。

  9. BUKERENYIJIADAJILIANG、ZENGJIAYONGYAOCISHUHUOYANZHANGLIAOCHENG,YIFANGXUJIZHONGDU。

足球彩票   10. YOUYUBENPINNENGYIZHIDACHANGGANJUNDESHENGZHANG,FANGAIBZUWEISHENGSUZAICHANGNEIDEHECHENG,GUSHIYONGBENPINCHAOGUOYIZHOUYISHANGZHE,YINGTONGSHIJIYUWEISHENGSUBYIYUFANGQIQUEFA。

足球彩票   11. RUYINFUYONGBENPINYINQIYESUANQUEFASHI,KETONGSHIFUYONGYESUANZHIJI,HOUZHEBINGBUGANRAOTMPDEKANGJUNHUOXING,YINXIJUNBINGBUNENGLIYONGYIHECHENGDEYESUAN,RUYOUGUSUIYIZHIZHENGXIANGFASHENG,YINGJITINGYONGBENPIN,BINGJIYUYESUAN3~6mgJIZHU,YIRI1CI,SHIYONG2RIHUOGENJUXUYAOYONGYAOZHIZAOXUEGONGNENGHUIFUZHENGCHANG,DUIZHANGQI、GUOLIANGSHIYONGBENPINZHEKEJIYUGAOJILIANGYESUANBINGYANZHANGLIAOCHENG。

  【孕妇及哺乳期妇女用药

  1. HUANGANYAOKETOUGUOTAIPANPINGZHANGZHITAIERTINEI,DONGWUSHIYANFAXIANYOUZHIJIZUOYONG。RENLEIYANJIUQUEFACHONGZUZILIAO,YUNFUYIBIMIANYINGYONG。

足球彩票   2. HUANGANYAOKEZIRUZHIZHONGFENMI,RUZHIZHONGNONGDUYUEKEDAMUTIXUEYAONONGDUDE50%~100%,YAOWUKENENGDUIYINGERCHANSHENGYINGXIANG;HUANGANYAOZAIPUTAOTANG-6-LINSUANTUOQINGMEIQUEFADEXINSHENGERZHONGDEYINGYONGYOUDAOZHIRONGXUEXINGPINXUEFASHENGDEKENENG。JIANYUSHANGSHUYUANYIN,BURUQIFUNVZANTINGYINGYONGBENPIN。

  【儿童用药

足球彩票   YIXIANZHUANYIMEIXITONGWEIFAYUWANSHAN,HUANGANYOULIXUENONGDUZENGGAO,YIZHIZENGJIALEHEHUANGDANFASHENGDEWEIXIANXING,YINCIGAILEIYAOWUZAIXINSHENGERJI2GEYUEYIXIAYINGERDEYINGYONGSHUJINJI。

  【LAONIANYONGYAO】

  LAONIANHUANZHEYINGYONGHUANGANYAOSHIFASHENGYANZHONGBULIANGFANYINGDEJIHUIZENGJIA。RUYANZHONGPIZHEN、GUSUIYIZHIHEXUEXIAOBANJIANSHAODENG。YINCILAONIANHUANZHEYIBIMIANYINGYONG,QUEYOUZHIZHENGSHIXUQUANHENGLIBIHOUJUEDING。

  【药物相互作用

  1. HANYOUNIAOJIANHUAYAOKEZENGJIABENPINZAIJIANXINGNIAOZHONGDERONGJIEDU,SHIPAIXIEZENGDUO.

  2. BUNENGYUDUIANJIBENJIASUANHEYONG,DUIANJIBENJIASUANKEDAITIBENPINBEIXIJUNSHEQU,LIANGZHEXIANGHUJIEKANG。

  3. XIALIEYAOWUYUBENPINTONGYONGSHI,BENPINKEQUDAIZHEIXIEYAOWUDEDANBAIJIEHEBUWEI,HUOYIZHIQIDAIXIE,YIZHIYAOWUZUOYONGSHIJIANYANZHANGHUOFASHENGDUXINGFANYING,YINCIDANGZHEIXIEYAOWUYUBENPINTONGSHIYINGYONG,HUOZAIYINGYONGBENPINZHIHOUSHIYONGSHIXUDIAOZHENGQIJILIANG。CILEIYAOWUBAOKUOKOUFUKANGNINGYAO、KOUFUJIANGXUETANGYAO、JIAANDIELING、BENTUOYINGNAHELIUPENTUONA。

  4. YUGUSUIYIZHIYAOHEYONGKENENGZENGQIANGCILEIYAOWUDUIZAOXUEXITONGDEBULIANGFANYING。RUBAIXIBAO、XUEXIAOBANJIANSHAODENG,RUQUEYOUZHIZHENGXULIANGYAOTONGYONGSHI,YINGYANMIGUANCHAKENENGFASHENGDEDUXINGFANYING。

足球彩票   5. YUBIYUNYAO(CIJISULEI)ZHANGSHIJIANHEYONGKEDAOZHIBIYUNDEKEKAOXINGJIANSHAO,BINGZENGJIAJINGQIWAICHUXUEDEJIHUI。

足球彩票   6. YURONGSHUANYAOWUHEYONGSHI,KENENGZENGDAQIQIANZAIDEDUXINGZUOYONG。

足球彩票   7. YUGANDUXINGYAOWUHEYONGSHI,KENENGYINQIGANDUXINGFASHENGLVDEZENGGAO。DUICILEIHUANZHEYOUQISHIYONGYAOSHIJIANJIAOZHANGJIYIWANGYOUGANBINGSHIZHEYINGJIANCEGANGONGNENG。

足球彩票   8. YUGUANGMINYAOWUHEYONGSHI,KENENGFASHENGGUANGMINZUOYONGXIANGJIA。

足球彩票   9. JIESHOUBENPINZHILIAOZHEDUIWEISHENGSUKDEXUYAOLIANGZENGJIA。

  10.BUYIYUWULUOTUOPINHEYONG,YINWULUOTUOPINZAISUANXINGNIAOZHONGKEFENJIECHANSHENGJIAQUAN,HOUZHEKEYUBENPINXINGCHENGBURONGXINGCHENDIANWU。SHIFASHENGJIEJINGNIAODEWEIXIANXINGZENGJIA。

  11.BENPINKEQUDAIBAOTAISONGDEXUEJIANGDANBAIJIEHEBUWEI,DANGLIANGZHETONGYONGSHIKEZENGQIANGBAOTAISONGDEZUOYONG。

  12. HUANGBITONG(sulfinpyrazone)YUBENPINHEYONGSHIKEJIANSHAOHOUZHEZISHENXIAOGUANDEFENMI,QIXUEYAONONGDUSHENGGAOQIECHIJIU,CONGERCHANSHENGDUXINGFANYING,YINCIZAIYINGYONGHUANGBITONGQIJIANHUOZAIYINGYONGQIZHILIAOHOUKENENGXUYAODIAOZHENGBENPINDEJILIANG。DANGHUANGBITONGLIAOCHENGJIAOZHANGSHI,DUIBENPINDEXUEYAONONGDUYIJINXINGJIANCE,YOUZHUYUJILIANGDEDIAOZHENG,BAOZHENGANQUANYONGYAO。

  13.BENPINZHONGDETMPKEYIZHIHUAFALINDEDAIXIEERZENGQIANGQIKANGNINGZUOYONG。

  14.BENPINZHONGDETMPYUHUANBAOSUHEYONGKEZENGJIASHENDUXING。

  15.LIFUPINGYUBENPINHEYONGSHI,KEMINGXIANSHIBENPINZHONGDETMPQINGCHUZENGJIAHEXUEQINGBANSHUAIQISUODUAN。

  16.BUYIYUKANGZHONGLIUYAO、2,4-ERANJIMIDINGLEIYAOWUHEYONG,YEBUYIZAIYINGYONGQITAYESUANJIEKANGYAOZHILIAODELIAOCHENGZHIJIANYINGYONGBENPIN,YINWEIYOUCHANSHENGGUSUIZAISHENGBULIANGHUOJUYOUHONGXIBAOPINXUEDEKENENG。

  17.BUYIYUANBENFENGHEYONG,YINANBENFENGYUBENPINZHONGDETMPHEYONGLIANGZHEXUEYAONONGDUJUNKESHENGGAO,ANBENFENGNONGDUDESHENGGAOSHIBULIANGFANYINGZENGDUOQIEJIAZHONG,YOUQISHIGAOTIEXUEHONGDANBAIXUEZHENGDEFASHENG。

  18.BIMIANYUQINGMEISULEIYAOWUHEYONG,YINWEIBENPINYOUKENENGGANRAOCILEIYAOWUDESHAJUNZUOYONG。

  【药物过量

足球彩票   HUANGANXUENONGDUBUYINGCHAOGUO200mg/ml,CHAOGUOCINONGDU,BULIANGFANYINGFASHENGLVZENGGAO,DUXINGZENGQIANG。GUOLIANGDUANQIFUYONGBENPINHUICHUXIANSHIYUBUZHEN、FUTONG、EXIN、OUTU、TOUYUN、TOUTONG、SHISHUI、SHENZHIBUQING、JINGSHENDICHEN、FARE、XUENIAO、JIEJINGNIAO、XUEYEJIBING、HUANGDAN、GUSUIYIZHIDENG。ZHANGQIGUOLIANGFUYONGBENPINHUIYINQIGUSUIYIZHI,ZAOCHENGXUEXIAOBAN、BAIXIBAODEJIANSHAOHEJUYOUHONGXIBAOXINGPINXUE。

  【药理毒理

  BENPINXIHUANGANJIAWUZUO(SMZ)、HUANGANMIDING(SD)HEJIAYANGBIANDING(TMP)DEFUFANGZHIJI。QIKANGJUNPUGUANG,KANGJUNZUOYONGQIANG,BINGJUYOUXIETONGYIJUNHUOSHAJUNZUOYONG,DUIDA DUOSHUGELANYANGXINGHEYINXINGJUN,BAOKUOFEICHANMEIJINPUJUN、HUANONGXINGLIANQIUJUN、FEIYANQIUJUN、DACHANGAIXIJUN、KELEIBOJUNSHU、SHAMENJUNSHU、BIANXINGGANJUNSHU、MOGENJUNSHU、ZHIHEJUNSHUDENGCHANGGANJUNKEXIJUN、LINQIUJUN、NAOMOYANQIUJUN、LIUGANSHIXUEGANJUNDENGJUNJUYOULIANGHAOKANGJUNHUOXING,JINNIANLAIXIJUNDUIBENPINNAIYAOXINGPUBIANCUNZAI,YOUQIZHIHEJUNSHUDENGCHANGGANJUNKEDEXIJUN,GUMUQIANLINCHUANGSHANGHENSHAOSHIYONG。CIWAIZAITIWAIDUIHUOLUANHUJUN、SHAYANYIYUANTIDENG、YIJULIANGHAOKANGJUNHUOXING。QIZUOYONGJIZHIWEISMZHESDJUNNENGYUDUIANJIBENJIASUANJINGZHENGERQINGYESUANHECHENGMEI,SHIXIJUNBUNENGHECHENGERQINGYESUAN,TMPZETONGGUOYIZHIXIJUNDEERQINGYESUANHAIYUANMEI,ZUAIERQINGYESUANHAIYUANCHENGSIQINGYESUAN。SANZHEHEYONGSHI,DUIXIJUNHECHENGSIQINGYESUANGUOCHENGQISHUANGZHONGZUDUANZUOYONG,GUQIKANGJUNZUOYONGJIAODANYAOZENGQIANG,BINGQIEDUITAMENNAIYAODEJUNZHUYEXIANGYINGJIANSHAO。

  【药代动力学

  BENPINKOUFUHOUZIWEICHANGDAOXISHOU,GUANGFANFENBUYUQUANSHENZUZHIHETIYE。YITOUGUOXUE-NAOJIYEPINGZHANGHETAIPANPINGZHANG。BENPINZHUYAOJINGSHENDAIXIE。

  【贮    藏】遮光,密封保存。

  【包    装】铝塑包装,纸盒;24片/盒。

  【有 效 期】24个月。

  【执行标准足球彩票】《中国药典》2005年版二部。

  【批准文号】国药准字H37022885

  【生产企业

  QIYEMINGCHENG:SHANDONGHAODANGJIAHAISENYAOYEYOUXIANGONGSI

  SHENGCHANDIZHI:SHANDONGSHENGRONGCHENGSHICHENGSHANDADAODONGSHOU

足球彩票   YOUZHENGBIANMA:264300

足球彩票   DIANHUAHAOMA:0631-7567210

足球彩票   CHUANZHENHAOMA:0631-7560211

  WANG    ZHI:http://yuefanghg.com

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邮编: 264300
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